/microbiology/viruses/{virus_code}/general

GET

/microbiology/viruses/1/general

GET

/microbiology/viruses/1/general

curl https://api.gideononline.com/microbiology/viruses/1/general \
     -H "Authorization: <apiKey>"

200Viruses_/microbiology/viruses/{virus_code}/general_example

{
  "data": {
    "id": 1,
    "drugs": [
      {
        "drug": "Brincidofovir",
        "auto_id": 2,
        "drug_code": 21276,
        "references": [
          {
            "href": "/references/p/35171015",
            "title": "Sensitivity of Human Mastadenovirus, the Causal Agent of Pharyngoconjunctival Fever, Epidemic Keratoconjunctivitis, and Hemorrhagic Cystitis in Immunocompromised Individuals, to Brincidofovir.",
            "citation": "Microbiol Spectr 2022 Feb 23;10(1):e0156921.",
            "short_citation": "",
            "reference_number": "p 35171015"
          }
        ]
      },
      {
        "drug": "Cidofovir",
        "auto_id": 1,
        "drug_code": 21206,
        "references": [
          {
            "href": "/references/p/30397065",
            "title": "Cidofovir Diphosphate Inhibits Adenovirus 5 DNA Polymerase via both Nonobligate Chain Termination and Direct Inhibition, and Polymerase Mutations Confer Cidofovir Resistance on Intact Virus.",
            "citation": "Antimicrob Agents Chemother 2019 Jan ;63(1)",
            "short_citation": "",
            "reference_number": "p 30397065"
          }
        ]
      }
    ],
    "images": [
      {
        "url": "https://cloudfront.gideononline.com/viruses-images/289fd7864ad51430bf921016de642961.png",
        "title": "T=25 icosahedral capsid protein",
        "source": "admin",
        "alt_text": "Virus image - T=25 icosahedral capsid protein",
        "provider": "ViralZone, SwissBioPics. DOI: 10.1093/nar/gkq901",
        "description": "The capsid is composed 60 asymmetric units made of 25 proteins (T=25), for a total of 1500 capsid proteins.\r\n\r\n\r\n\r\n",
        "image_category": "structure",
        "image_file_name": "289fd7864ad51430bf921016de642961.png"
      },
      {
        "url": "https://cloudfront.gideononline.com/viruses-images/3f7a01c18ee59353bfa2781c8ae2b5ba.png",
        "title": "Structure of Adenovirus (now: Mastadenovirus)",
        "source": "admin",
        "alt_text": "Virus image - Structure of Adenovirus (now: Mastadenovirus)",
        "provider": "M.M.Y. Waye, C.W. Sing, 2010. DOI: 10.3390/ph3103343",
        "description": "",
        "image_category": "structure",
        "image_file_name": "3f7a01c18ee59353bfa2781c8ae2b5ba.png"
      },
      {
        "url": "https://cloudfront.gideononline.com/viruses-images/4a37318a9c452dc58a30832df3ff2a72.png",
        "title": "Human adenovirus type C replication cycle",
        "source": "admin",
        "alt_text": "Virus image - Human adenovirus type C replication cycle",
        "provider": "ViralZone, SwissBioPics. DOI: 10.1093/nar/gkq901",
        "description": "",
        "image_category": "mechanism",
        "image_file_name": "4a37318a9c452dc58a30832df3ff2a72.png"
      },
      {
        "url": "https://cloudfront.gideononline.com/viruses-images/7c84de0c43463e5e35aa6b400f14dafa.png",
        "title": "Mastadenovirus virion",
        "source": "admin",
        "alt_text": "Virus image - Mastadenovirus virion",
        "provider": "ViralZone, SwissBioPics. DOI: 10.1093/nar/gkq901",
        "description": "Non-enveloped capsid with a pseudo T=25 icosahedral symmetry . The capsid diameter is about 90 nm. The capsid shell consists of 720 hexon subunits arranged as 240 trimers and 12 vertex penton capsomers each with a fiber protruding from the surface.",
        "image_category": "structure",
        "image_file_name": "7c84de0c43463e5e35aa6b400f14dafa.png"
      },
      {
        "url": "https://cloudfront.gideononline.com/viruses-images/965d77c3e49092bf437088064d619509.png",
        "title": "Adenovirus (now: Mastadenovirus) replication and infection pathway",
        "source": "admin",
        "alt_text": "Virus image - Adenovirus (now: Mastadenovirus) replication and infection pathway",
        "provider": "M.M.Y. Waye, C.W. Sing, 2010. DOI: 10.3390/ph3103343",
        "description": "",
        "image_category": "mechanism",
        "image_file_name": "965d77c3e49092bf437088064d619509.png"
      }
    ],
    "vectors": [],
    "diseases": [
      {
        "auto_id": 150,
        "disease": "Adenovirus infection",
        "references": [],
        "disease_code": 10030
      }
    ],
    "synonyms": [
      "Adenovirus",
      "AdV",
      "HAdV"
    ],
    "vaccines": [
      {
        "auto_id": 1,
        "vaccine": "Adenovirus vaccine",
        "references": [
          {
            "href": "/references/p/17728025",
            "title": "Role of U.S. military research programs in the development of U.S.-licensed vaccines for naturally occurring infectious diseases.",
            "citation": "Vaccine 2007 Oct 10;25(41):7017-30.",
            "short_citation": "",
            "reference_number": "p 17728025"
          },
          {
            "href": "/references/p/15174954",
            "title": "Vaccines for the prevention of respiratory viral infections: problems and current status.",
            "citation": "Expert Opin Investig Drugs 2004 Jun ;13(6):681-9.",
            "short_citation": "",
            "reference_number": "p 15174954"
          },
          {
            "href": "/references/p/2560582",
            "title": "Current use and future directions of adenovirus vaccine.",
            "citation": "Semin Respir Infect 1989 Dec ;4(4):299-303.",
            "short_citation": "",
            "reference_number": "p 2560582"
          },
          {
            "href": "/references/p/31548014",
            "title": "Adverse events following adenovirus type 4 and type 7 vaccine, live, oral in the Vaccine Adverse Event Reporting System (VAERS), United States, October 2011-July 2018.",
            "citation": "Vaccine 2019 Sep 20;",
            "short_citation": "",
            "reference_number": "p 31548014"
          }
        ],
        "vaccine_code": 30015
      }
    ],
    "vehicles": [
      {
        "auto_id": 188,
        "references": [
          {
            "href": "/references/s/d 579325",
            "title": "",
            "citation": "",
            "short_citation": "",
            "reference_number": "scd 579325"
          }
        ],
        "vehicle_class": "Aerosol "
      },
      {
        "auto_id": 189,
        "references": [
          {
            "href": "/references/s/d 579325",
            "title": "",
            "citation": "",
            "short_citation": "",
            "reference_number": "scd 579325"
          }
        ],
        "vehicle_class": "Fecal-oral route"
      }
    ],
    "etymology": [
      {
        "term": "Mastadenovirus",
        "meaning": "Greek, <i>mastos</i> - breast (hence, mammal); and adeno (virus originallly isolated from the adenoids)",
        "references": []
      }
    ],
    "is_italic": 1,
    "structure": "Mastadenovirus particles are icosahedral. They range in size from 70 to 100 nanometers. They are made up of hexons that form the shell's faces and edges and pentons at the vertices (with fibrous projections). The viral genome is double-stranded, linear DNA, and its size ranges from 26 to 45 kbp. It has inverted terminal repeats between 36 to 200 bp in length. The terminal protein is covalently linked to the 5' end. Viruses from the <i>Mastadenovirus</i> genus encode approximately 16 common genes. \"Genus-specific genes\" are mainly found in the E1 and E4 regions. {p 14573794} {p 34063479} {p 14573794} {p 32236817}",
    "reservoirs": [
      {
        "auto_id": 1,
        "references": [
          {
            "href": "/references/p/34473804",
            "title": "What is the risk of a deadly adenovirus pandemic?",
            "citation": "PLoS Pathog 2021 Sep ;17(9):e1009814.",
            "short_citation": "",
            "reference_number": "p 34473804"
          }
        ],
        "reservoir_class": "Bat",
        "reservoir_entity": "Bats ",
        "reservoir_entity_latin": "Order: Chiroptera"
      },
      {
        "auto_id": 2,
        "references": [
          {
            "href": "/references/p/38338959",
            "title": "Chicken Interferon-Alpha and -Lambda Exhibit Antiviral Effects against Fowl Adenovirus Serotype 4 in Leghorn Male Hepatocellular Cells.",
            "citation": "Int J Mol Sci 2024 Jan 30;25(3)",
            "short_citation": "",
            "reference_number": "p 38338959"
          }
        ],
        "reservoir_class": "Bird",
        "reservoir_entity": "string",
        "reservoir_entity_latin": "string"
      },
      {
        "auto_id": 211,
        "references": [
          {
            "href": "/references/c/c 566071",
            "title": "",
            "citation": "",
            "short_citation": "",
            "reference_number": "cdc 566071"
          }
        ],
        "reservoir_class": "Human",
        "reservoir_entity": "Human",
        "reservoir_entity_latin": "<i>Homo sapiens</i>"
      },
      {
        "auto_id": 7,
        "references": [
          {
            "href": "/references/p/36277107",
            "title": "Simian adenoviruses: Molecular and serological survey in monkeys and humans in Thailand.",
            "citation": "One Health 2022 Dec ;15:100434.",
            "short_citation": "",
            "reference_number": "p 36277107"
          }
        ],
        "reservoir_class": "Nonhuman primate",
        "reservoir_entity": "string",
        "reservoir_entity_latin": "string"
      },
      {
        "auto_id": 8,
        "references": [
          {
            "href": "/references/p/225288",
            "title": "Adenovirus types 8 and 19 infection of rabbit corneal organ cultures.",
            "citation": "Invest Ophthalmol Vis Sci 1979 Sep ;18(9):956-63.",
            "short_citation": "",
            "reference_number": "p 225288"
          }
        ],
        "reservoir_class": "Rabbit",
        "reservoir_entity": "string",
        "reservoir_entity_latin": "string"
      },
      {
        "auto_id": 13,
        "references": [
          {
            "href": "/references/p/8380066",
            "title": "Pathogenesis of adenovirus type 5 pneumonia in cotton rats (Sigmodon hispidus).",
            "citation": "J Virol 1993 Jan ;67(1):101-11.",
            "short_citation": "",
            "reference_number": "p 8380066"
          }
        ],
        "reservoir_class": "Rodent",
        "reservoir_entity": "string",
        "reservoir_entity_latin": "string"
      },
      {
        "auto_id": 210,
        "references": [
          {
            "href": "/references/p/31747467",
            "title": "Adenoviruses across the animal kingdom: a walk in the zoo.",
            "citation": "FEBS Lett 2019 Nov 20;",
            "short_citation": "",
            "reference_number": "p 31747467"
          }
        ],
        "reservoir_class": "Reptile",
        "reservoir_entity": "Reptiles ",
        "reservoir_entity_latin": "Class: Reptilia "
      }
    ],
    "virus_name": "Mastadenovirus",
    "genome_type": "Double-stranded DNA",
    "is_zoonotic": 1,
    "entry_mechanism": "Viruses from the genus <i>Mastadenovirus</i> enter into a host cell by binding to the host cell's receptors. This occurs due to the action of a major capsid protein. After attachment, the virus uncoats, and the viral genome is released into the host cell. The virus is eventually trafficked to the nucleus of the cell. {p 31283442} {p 31784892} {p 31758703} {p 35434852} ",
    "replication_mechanism": "Once in the nucleus, the virus triggers early gene expression. The viral polymerase then elongates the nascent strand and displaces the existing strand. This leads to the formation of a new double-stranded DNA (dsDNA) template. This process is made possible by DBP, which oligomerizes alongside the now displaced single-stranded DNA (ssDNA). The new dsDNA genome and displaced ssDNA intermediate work as templates for continued replication. Viral genomes accumulate in the nucleus and form virus-induced postreplication (ViPR) bodies. {p 2894680} {p 12747549} {p 15273278} {p 11457998} {p 9469832} {p 2838479} {p 1291241} {p 7988575}",
    "genome_type_references": "ncfbt 458815"
  }
}

Returns the following information of the selected virus.

virus_name: Name of the virus.
is_italic: Indicates whether or not the virus name should be italicized.
is_zoonotic: Indicates whether the virus can be transmitted from animals to humans.
etymology: Provides the origin and historical background of the virus name.
genome_type: Describes the genetic material of the virus, such as RNA or DNA
.entry_mechanism: Explains how the virus enters the host cell.
synonyms: Lists alternative names and terms for the virus.
replication_mechanism: Describes the process by which the virus replicates within the host.
diseases: Identifies the diseases caused by the virus.
drugs: Lists antiviral drugs effective against the virus.
vaccines: Provides information on vaccines available for the virus.
structure: Details the physical structure of the virus.

Authentication

Authorizationstring

API Key authentication via header

Response headers

UpgradestringOptional

X-Powered-BystringOptional

Access-Control-Allow-OriginstringOptional

Response

dataobject